Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Spirit Airlines

The cheapest airline(s) flying from Saint Louis to Santa Ana is Spirit Airlines.

  • Spirit Airlines Spirit Airlines
  • Frontier Airlines Frontier Airlines
  • Delta Air Lines Delta Air Lines
  • American Airlines American Airlines
  • United Airlines United Airlines
  • Alaska Airlines Alaska Airlines
Cheapest Month No data available
No data available

Currently we do not have data for this specific route. Please try to search directly from our search form

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Cheapest Day of the Week Friday

The cheapest day(s) of the week to fly from Saint Louis to Santa Ana is Friday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday
Cheapest Time 4pm

The cheapest time of the day to fly from Saint Louis to Santa Ana is in the afternoon.

Early Morning 12:01am - 06:00am
Morning 6:01am - 12:00pm
Afternoon 12:01pm - 6:00pm
Evening 6:01pm to 12:00am
12am
6am
12pm
6pm

Flight Schedules

Last Updated: Thu, 2 May, 2024

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  • Total Duration
    • Shortest
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  • Availability
    • M
    • T
    • W
    • T
    • F
    • S
    • S
  • 16:45 - 20:10
    STL - SNA
  • 16:45 (STL)St Louis Lambert Intl Airport
  • 20:10 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 2012)Boeing 737 700
  • 5h 25m
  • Direct
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • Boeing 737 700

Connecting Flights

  • 05:35 - 06:55
    STL - DEN
    09:20 - 10:45
    DEN - SNA
  • 05:35 (STL)St Louis Lambert Intl Airport
    09:20 (DEN)Denver Intl Airport
  • 06:55 (DEN)Denver Intl Airport
    10:45 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 652)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 1708)Boeing 737 700
  • 7h 10m (2h 25m)
  • DEN Denver 2h 25m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 05:40 - 07:20
    STL - DAL
    09:50 - 11:05
    DAL - SNA
  • 05:40 (STL)St Louis Lambert Intl Airport
    09:50 (DAL)Dallas/Fort Worth Love Field Airport
  • 07:20 (DAL)Dallas/Fort Worth Love Field Airport
    11:05 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 5073)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 1957)Boeing 737 700
  • 7h 25m (2h 30m)
  • DAL Dallas 2h 30m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 05:45 - 07:10
    STL - PHX
    08:45 - 10:15
    PHX - SNA
  • 05:45 (STL)St Louis Lambert Intl Airport
    08:45 (PHX)Phoenix Sky Harbor Intl Airport
  • 07:10 (PHX)Phoenix Sky Harbor Intl Airport
    10:15 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 3900)Boeing 737 800
    Southwest Airlines (WN 5029)Boeing 737 700
  • 6h 30m (1h 35m)
  • PHX Phoenix 1h 35m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 05:45 - 07:10
    STL - PHX
    10:55 - 12:20
    PHX - SNA
  • 05:45 (STL)St Louis Lambert Intl Airport
    10:55 (PHX)Phoenix Sky Harbor Intl Airport
  • 07:10 (PHX)Phoenix Sky Harbor Intl Airport
    12:20 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 3900)Boeing 737 800
    Southwest Airlines (WN 255)Boeing 737 700
  • 8h 35m (3h 45m)
  • PHX Phoenix 3h 45m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 06:00 - 07:20
    STL - DEN
    09:20 - 10:45
    DEN - SNA
  • 06:00 (STL)St Louis Lambert Intl Airport
    09:20 (DEN)Denver Intl Airport
  • 07:20 (DEN)Denver Intl Airport
    10:45 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 652)Boeing 737 700
    Southwest Airlines (WN 1708)Boeing 737 700
  • 6h 45m (2h)
  • DEN Denver 2h
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 06:05 - 07:25
    STL - PHX
    11:05 - 12:25
    PHX - SNA
  • 06:05 (STL)St Louis Lambert Intl Airport
    11:05 (PHX)Phoenix Sky Harbor Intl Airport
  • 07:25 (PHX)Phoenix Sky Harbor Intl Airport
    12:25 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 3900)Boeing 737 700
    Southwest Airlines (WN 255)Boeing 737 700
  • 8h 20m (3h 40m)
  • PHX Phoenix 3h 40m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 06:10 - 07:45
    STL - LAS
    08:35 - 09:45
    LAS - SNA
  • 06:10 (STL)St Louis Lambert Intl Airport
    08:35 (LAS)Las Vegas McCarran International Airport
  • 07:45 (LAS)Las Vegas McCarran International Airport
    09:45 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 2256)Boeing 737 700
    Southwest Airlines (WN 2458)Boeing 737 700
  • 5h 35m (50m)
  • LAS Las Vegas 50m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 06:10 - 07:45
    STL - LAS
    11:05 - 12:15
    LAS - SNA
  • 06:10 (STL)St Louis Lambert Intl Airport
    11:05 (LAS)Las Vegas McCarran International Airport
  • 07:45 (LAS)Las Vegas McCarran International Airport
    12:15 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 2256)Boeing 737 700
    Southwest Airlines (WN 4550)Boeing 737 700
  • 8h 05m (3h 20m)
  • LAS Las Vegas 3h 20m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 11:05 - 12:15
    LAS - SNA
    06:15 - 07:30
    STL - DEN
  • 11:05 (LAS)Las Vegas McCarran International Airport
    06:15 (STL)St Louis Lambert Intl Airport
  • 12:15 (SNA)Santa Ana John Wayne Airport
    07:30 (DEN)Denver Intl Airport
  • Southwest Airlines (WN 4550)Boeing 737 700
    Southwest Airlines (WN 652)Boeing 737 800
  • 8h (2h 40m)
  • SNA Santa Ana 2h 40m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 06:15 - 07:30
    STL - DEN
    09:35 - 11:00
    DEN - SNA
  • 06:15 (STL)St Louis Lambert Intl Airport
    09:35 (DEN)Denver Intl Airport
  • 07:30 (DEN)Denver Intl Airport
    11:00 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 652)Boeing 737 800
    Southwest Airlines (WN 1708)Boeing 737 700
  • 6h 45m (2h 05m)
  • DEN Denver 2h 05m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 06:25 - 08:00
    STL - LAS
    11:30 - 12:40
    LAS - SNA
  • 06:25 (STL)St Louis Lambert Intl Airport
    11:30 (LAS)Las Vegas McCarran International Airport
  • 08:00 (LAS)Las Vegas McCarran International Airport
    12:40 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 669)Boeing 737 700
    Southwest Airlines (WN 495)Boeing 737 700
  • 8h 15m (3h 30m)
  • LAS Las Vegas 3h 30m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 11:30 - 12:40
    LAS - SNA
    06:35 - 07:50
    STL - PHX
  • 11:30 (LAS)Las Vegas McCarran International Airport
    06:35 (STL)St Louis Lambert Intl Airport
  • 12:40 (SNA)Santa Ana John Wayne Airport
    07:50 (PHX)Phoenix Sky Harbor Intl Airport
  • Southwest Airlines (WN 495)Boeing 737 700
    Southwest Airlines (WN 3900)Boeing 737 700
  • 8h 05m (2h 30m)
  • SNA Santa Ana 2h 30m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 06:35 - 07:50
    STL - PHX
    09:15 - 10:35
    PHX - SNA
  • 06:35 (STL)St Louis Lambert Intl Airport
    09:15 (PHX)Phoenix Sky Harbor Intl Airport
  • 07:50 (PHX)Phoenix Sky Harbor Intl Airport
    10:35 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 3900)Boeing 737 700
    Southwest Airlines (WN 5029)Boeing 737 700
  • 6h (1h 25m)
  • PHX Phoenix 1h 25m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 07:00 - 08:20
    STL - DEN
    09:25 - 13:00
    DEN - SNA
  • 07:00 (STL)St Louis Lambert Intl Airport
    09:25 (DEN)Denver Intl Airport
  • 08:20 (DEN)Denver Intl Airport
    13:00 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 463)Boeing 737 700
    Southwest Airlines (WN 5766)Boeing 737 700
  • 8h (1h 05m)
  • DEN Denver 1h 05m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 07:00 - 08:20
    STL - DEN
    09:20 - 10:45
    DEN - SNA
  • 07:00 (STL)St Louis Lambert Intl Airport
    09:20 (DEN)Denver Intl Airport
  • 08:20 (DEN)Denver Intl Airport
    10:45 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 463)Boeing 737 700
    Southwest Airlines (WN 1708)Boeing 737 700
  • 5h 45m (1h)
  • DEN Denver 1h
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 07:25 - 08:45
    STL - DEN
    12:45 - 14:10
    DEN - SNA
  • 07:25 (STL)St Louis Lambert Intl Airport
    12:45 (DEN)Denver Intl Airport
  • 08:45 (DEN)Denver Intl Airport
    14:10 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 463)Boeing 737 700
    Southwest Airlines (WN 3500)Boeing 737 700
  • 8h 45m (4h)
  • DEN Denver 4h
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 07:50 - 09:30
    STL - DAL
    13:35 - 14:50
    DAL - SNA
  • 07:50 (STL)St Louis Lambert Intl Airport
    13:35 (DAL)Dallas/Fort Worth Love Field Airport
  • 09:30 (DAL)Dallas/Fort Worth Love Field Airport
    14:50 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 5073)Boeing 737 700
    Southwest Airlines (WN 1957)Boeing 737 700
  • 9h (4h 05m)
  • DAL Dallas 4h 05m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 08:20 - 09:40
    STL - DEN
    13:10 - 14:35
    DEN - SNA
  • 08:20 (STL)St Louis Lambert Intl Airport
    13:10 (DEN)Denver Intl Airport
  • 09:40 (DEN)Denver Intl Airport
    14:35 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 463)Boeing 737 700
    Southwest Airlines (WN 1752)Boeing 737 700
  • 8h 15m (3h 30m)
  • DEN Denver 3h 30m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 08:25 - 10:10
    STL - DAL
    12:45 - 14:05
    DAL - SNA
  • 08:25 (STL)St Louis Lambert Intl Airport
    12:45 (DAL)Dallas/Fort Worth Love Field Airport
  • 10:10 (DAL)Dallas/Fort Worth Love Field Airport
    14:05 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 1463)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 1957)Boeing 737 700
  • 7h 40m (2h 35m)
  • DAL Dallas 2h 35m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 08:55 - 12:15
    STL - DEN
    13:10 - 14:35
    DEN - SNA
  • 08:55 (STL)St Louis Lambert Intl Airport
    13:10 (DEN)Denver Intl Airport
  • 12:15 (DEN)Denver Intl Airport
    14:35 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 3317)Boeing 737 700
    Southwest Airlines (WN 1752)Boeing 737 700
  • 7h 40m (55m)
  • DEN Denver 55m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 13:40 - 14:55
    PHX - SNA
    09:00 - 10:40
    STL - DAL
  • 13:40 (PHX)Phoenix Sky Harbor Intl Airport
    09:00 (STL)St Louis Lambert Intl Airport
  • 14:55 (SNA)Santa Ana John Wayne Airport
    10:40 (DAL)Dallas/Fort Worth Love Field Airport
  • Southwest Airlines (WN 4566)Boeing 737 700
    Southwest Airlines (WN 1463)Boeing 737 800
  • 7h 55m (2h 30m)
  • SNA Santa Ana 2h 30m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 09:20 - 10:45
    STL - DEN
    13:05 - 14:30
    DEN - SNA
  • 09:20 (STL)St Louis Lambert Intl Airport
    13:05 (DEN)Denver Intl Airport
  • 10:45 (DEN)Denver Intl Airport
    14:30 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 1792)Boeing 737 700
    Southwest Airlines (WN 1890)Boeing 737 700
  • 7h 10m (2h 20m)
  • DEN Denver 2h 20m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 09:30 - 11:00
    STL - LAS
    13:35 - 14:50
    LAS - SNA
  • 09:30 (STL)St Louis Lambert Intl Airport
    13:35 (LAS)Las Vegas McCarran International Airport
  • 11:00 (LAS)Las Vegas McCarran International Airport
    14:50 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 2592)Boeing 737 800
    Southwest Airlines (WN 495)Boeing 737 700
  • 7h 20m (2h 35m)
  • LAS Las Vegas 2h 35m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 09:45 - 11:25
    STL - DAL
    13:40 - 14:55
    DAL - SNA
  • 09:45 (STL)St Louis Lambert Intl Airport
    13:40 (DAL)Dallas/Fort Worth Love Field Airport
  • 11:25 (DAL)Dallas/Fort Worth Love Field Airport
    14:55 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 4631)Boeing 737 700
    Southwest Airlines (WN 3500)Boeing 737 700
  • 7h 10m (2h 15m)
  • DAL Dallas 2h 15m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 10:00 - 12:45
    STL - LAS
    14:30 - 15:55
    LAS - SNA
  • 10:00 (STL)St Louis Lambert Intl Airport
    14:30 (LAS)Las Vegas McCarran International Airport
  • 12:45 (LAS)Las Vegas McCarran International Airport
    15:55 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 2249)Boeing 737 700
    Southwest Airlines (WN 495)Boeing 737 700
  • 7h 55m (1h 45m)
  • LAS Las Vegas 1h 45m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 10:00 - 11:35
    STL - LAS
    14:25 - 15:40
    LAS - SNA
  • 10:00 (STL)St Louis Lambert Intl Airport
    14:25 (LAS)Las Vegas McCarran International Airport
  • 11:35 (LAS)Las Vegas McCarran International Airport
    15:40 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 2592)Boeing 737 800
    Southwest Airlines (WN 4554)Boeing 737 700
  • 7h 40m (2h 50m)
  • LAS Las Vegas 2h 50m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 14:30 - 15:55
    LAS - SNA
    10:00 - 11:10
    STL - MCI
  • 14:30 (LAS)Las Vegas McCarran International Airport
    10:00 (STL)St Louis Lambert Intl Airport
  • 15:55 (SNA)Santa Ana John Wayne Airport
    11:10 (MCI)Kansas City International Airport
  • Southwest Airlines (WN 495)Boeing 737 700
    Southwest Airlines (WN 5794)Boeing 737 800
  • 7h 55m (2h 15m)
  • SNA Santa Ana 2h 15m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 10:00 - 13:00
    STL - LAS
    14:30 - 15:55
    LAS - SNA
  • 10:00 (STL)St Louis Lambert Intl Airport
    14:30 (LAS)Las Vegas McCarran International Airport
  • 13:00 (LAS)Las Vegas McCarran International Airport
    15:55 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 2714)Boeing 737 700
    Southwest Airlines (WN 495)Boeing 737 700
  • 7h 55m (1h 30m)
  • LAS Las Vegas 1h 30m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 10:00 - 11:35
    STL - LAS
    13:10 - 14:25
    LAS - SNA
  • 10:00 (STL)St Louis Lambert Intl Airport
    13:10 (LAS)Las Vegas McCarran International Airport
  • 11:35 (LAS)Las Vegas McCarran International Airport
    14:25 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 2592)Boeing 737 800
    Southwest Airlines (WN 495)Boeing 737 700
  • 6h 25m (1h 35m)
  • LAS Las Vegas 1h 35m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 10:00 - 12:30
    STL - PHX
    13:25 - 14:40
    PHX - SNA
  • 10:00 (STL)St Louis Lambert Intl Airport
    13:25 (PHX)Phoenix Sky Harbor Intl Airport
  • 12:30 (PHX)Phoenix Sky Harbor Intl Airport
    14:40 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 233)Boeing 737 700
    Southwest Airlines (WN 4569)Boeing 737 700
  • 6h 40m (55m)
  • PHX Phoenix 55m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 10:05 - 11:45
    STL - LAS
    15:55 - 17:10
    LAS - SNA
  • 10:05 (STL)St Louis Lambert Intl Airport
    15:55 (LAS)Las Vegas McCarran International Airport
  • 11:45 (LAS)Las Vegas McCarran International Airport
    17:10 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 2256)Boeing 737 800
    Southwest Airlines (WN 4554)Boeing 737 700
  • 9h 05m (4h 10m)
  • LAS Las Vegas 4h 10m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 10:05 - 11:45
    STL - LAS
    13:05 - 14:15
    LAS - SNA
  • 10:05 (STL)St Louis Lambert Intl Airport
    13:05 (LAS)Las Vegas McCarran International Airport
  • 11:45 (LAS)Las Vegas McCarran International Airport
    14:15 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 2256)Boeing 737 800
    Southwest Airlines (WN 962)Boeing 737 700
  • 6h 10m (1h 20m)
  • LAS Las Vegas 1h 20m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 10:05 - 11:25
    STL - DEN
    15:20 - 16:45
    DEN - SNA
  • 10:05 (STL)St Louis Lambert Intl Airport
    15:20 (DEN)Denver Intl Airport
  • 11:25 (DEN)Denver Intl Airport
    16:45 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 1871)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 4538)Boeing 737 700
  • 8h 40m (3h 55m)
  • DEN Denver 3h 55m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 10:05 - 11:25
    STL - DEN
    13:10 - 14:35
    DEN - SNA
  • 10:05 (STL)St Louis Lambert Intl Airport
    13:10 (DEN)Denver Intl Airport
  • 11:25 (DEN)Denver Intl Airport
    14:35 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 1871)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 1752)Boeing 737 700
  • 6h 30m (1h 45m)
  • DEN Denver 1h 45m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 10:15 - 12:15
    STL - AUS
    16:00 - 17:10
    AUS - SNA
  • 10:15 (STL)St Louis Lambert Intl Airport
    16:00 (AUS)Austin-Bergstrom International Airport
  • 12:15 (AUS)Austin-Bergstrom International Airport
    17:10 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 3299)Boeing 737 800
    Southwest Airlines (WN 2433)Boeing 737 700
  • 8h 55m (3h 45m)
  • AUS Austin 3h 45m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 10:15 - 12:10
    STL - SJD
    14:20 - 16:55
    SJD - SNA
  • 10:15 (STL)St Louis Lambert Intl Airport
    14:20 (SJD)San Jose Cabo Airport
  • 12:10 (SJD)San Jose Cabo Airport
    16:55 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 6231)Boeing 737 800
    Southwest Airlines (WN 625)Boeing 737 700
  • 8h 40m (2h 10m)
  • SJD San Jose Cabo 2h 10m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 10:20 - 11:35
    STL - PHX
    16:25 - 17:45
    PHX - SNA
  • 10:20 (STL)St Louis Lambert Intl Airport
    16:25 (PHX)Phoenix Sky Harbor Intl Airport
  • 11:35 (PHX)Phoenix Sky Harbor Intl Airport
    17:45 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 1945)Boeing 737 700
    Southwest Airlines (WN 1555)Boeing 737 700
  • 9h 25m (4h 50m)
  • PHX Phoenix 4h 50m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 15:10 - 16:25
    SJC - SNA
    10:35 - 11:55
    STL - DEN
  • 15:10 (SJC)San Jose International Airport
    10:35 (STL)St Louis Lambert Intl Airport
  • 16:25 (SNA)Santa Ana John Wayne Airport
    11:55 (DEN)Denver Intl Airport
  • Southwest Airlines (WN 153)Boeing 737 700
    Southwest Airlines (WN 1871)Boeing 737 Max 8 Passenger
  • 7h 50m (1h 40m)
  • SNA Santa Ana 1h 40m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 10:35 - 11:55
    STL - DEN
    16:15 - 17:40
    DEN - SNA
  • 10:35 (STL)St Louis Lambert Intl Airport
    16:15 (DEN)Denver Intl Airport
  • 11:55 (DEN)Denver Intl Airport
    17:40 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 1871)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 1708)Boeing 737 700
  • 9h 05m (4h 20m)
  • DEN Denver 4h 20m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 15:20 - 16:45
    DEN - SNA
    10:35 - 11:40
    STL - MCI
  • 15:20 (DEN)Denver Intl Airport
    10:35 (STL)St Louis Lambert Intl Airport
  • 16:45 (SNA)Santa Ana John Wayne Airport
    11:40 (MCI)Kansas City International Airport
  • Southwest Airlines (WN 4538)Boeing 737 700
    Southwest Airlines (WN 5794)Boeing 737 800
  • 8h 10m (2h 50m)
  • SNA Santa Ana 2h 50m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 10:35 - 11:55
    STL - DEN
    12:45 - 14:10
    DEN - SNA
  • 10:35 (STL)St Louis Lambert Intl Airport
    12:45 (DEN)Denver Intl Airport
  • 11:55 (DEN)Denver Intl Airport
    14:10 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 1871)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 3500)Boeing 737 700
  • 5h 35m (50m)
  • DEN Denver 50m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 10:35 - 13:15
    STL - LAS
    14:25 - 15:40
    LAS - SNA
  • 10:35 (STL)St Louis Lambert Intl Airport
    14:25 (LAS)Las Vegas McCarran International Airport
  • 13:15 (LAS)Las Vegas McCarran International Airport
    15:40 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 2249)Boeing 737 700
    Southwest Airlines (WN 4554)Boeing 737 700
  • 7h 05m (1h 10m)
  • LAS Las Vegas 1h 10m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 10:40 - 14:10
    STL - AUS
    15:10 - 16:25
    AUS - SNA
  • 10:40 (STL)St Louis Lambert Intl Airport
    15:10 (AUS)Austin-Bergstrom International Airport
  • 14:10 (AUS)Austin-Bergstrom International Airport
    16:25 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 5794)Boeing 737 700
    Southwest Airlines (WN 5046)Boeing 737 700
  • 7h 45m (1h)
  • AUS Austin 1h
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 10:45 - 13:10
    STL - PHX
    14:20 - 15:30
    PHX - SNA
  • 10:45 (STL)St Louis Lambert Intl Airport
    14:20 (PHX)Phoenix Sky Harbor Intl Airport
  • 13:10 (PHX)Phoenix Sky Harbor Intl Airport
    15:30 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 233)Boeing 737 700
    Southwest Airlines (WN 4569)Boeing 737 700
  • 6h 45m (1h 10m)
  • PHX Phoenix 1h 10m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 15:20 - 16:45
    DEN - SNA
    10:45 - 12:00
    STL - OMA
  • 15:20 (DEN)Denver Intl Airport
    10:45 (STL)St Louis Lambert Intl Airport
  • 16:45 (SNA)Santa Ana John Wayne Airport
    12:00 (OMA)Omaha Eppley Airfield Airport
  • Southwest Airlines (WN 4538)Boeing 737 700
    Southwest Airlines (WN 988)Boeing 737 800
  • 8h (2h 45m)
  • SNA Santa Ana 2h 45m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 10:45 - 12:50
    STL - AUS
    16:20 - 17:35
    AUS - SNA
  • 10:45 (STL)St Louis Lambert Intl Airport
    16:20 (AUS)Austin-Bergstrom International Airport
  • 12:50 (AUS)Austin-Bergstrom International Airport
    17:35 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 3299)Boeing 737 700
    Southwest Airlines (WN 4543)Boeing 737 700
  • 8h 50m (3h 30m)
  • AUS Austin 3h 30m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 10:50 - 12:55
    STL - AUS
    15:10 - 16:25
    AUS - SNA
  • 10:50 (STL)St Louis Lambert Intl Airport
    15:10 (AUS)Austin-Bergstrom International Airport
  • 12:55 (AUS)Austin-Bergstrom International Airport
    16:25 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 3299)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 5046)Boeing 737 700
  • 7h 35m (2h 15m)
  • AUS Austin 2h 15m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 11:00 - 12:20
    STL - DEN
    13:05 - 14:30
    DEN - SNA
  • 11:00 (STL)St Louis Lambert Intl Airport
    13:05 (DEN)Denver Intl Airport
  • 12:20 (DEN)Denver Intl Airport
    14:30 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 1871)Boeing 737 800
    Southwest Airlines (WN 1890)Boeing 737 700
  • 5h 30m (45m)
  • DEN Denver 45m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 11:40 - 13:00
    STL - PHX
    14:20 - 15:30
    PHX - SNA
  • 11:40 (STL)St Louis Lambert Intl Airport
    14:20 (PHX)Phoenix Sky Harbor Intl Airport
  • 13:00 (PHX)Phoenix Sky Harbor Intl Airport
    15:30 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 3901)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 4569)Boeing 737 700
  • 5h 50m (1h 20m)
  • PHX Phoenix 1h 20m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 12:00 - 13:20
    STL - PHX
    17:45 - 19:00
    PHX - SNA
  • 12:00 (STL)St Louis Lambert Intl Airport
    17:45 (PHX)Phoenix Sky Harbor Intl Airport
  • 13:20 (PHX)Phoenix Sky Harbor Intl Airport
    19:00 (SNA)Santa Ana John Wayne Airport
  • Southwest Airlines (WN 3901)Boeing 737 700
    Southwest Airlines (WN 1555)Boeing 737 700
  • 9h (4h 25m)
  • PHX Phoenix 4h 25m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
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What’s the fastest flight time from Saint Louis to Santa Ana?

The fastest flight time for direct flights from Saint Louis to Santa Ana is 5 hours 25 minutes. Check latest flight schedules & prices on Wego.

What’s the most popular airline flying from Saint Louis to Santa Ana?

The most popular airline flying from Saint Louis to Santa Ana is American Airlines. Find the latest flight deals on Wego.

How far is Santa Ana from Saint Louis?

The flight distance between Saint Louis and Santa Ana is 2532km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 05:35. The last flight of the day departs at 05:35. See the full list of flight times on Wego.

How many airlines offer direct flights from Saint Louis to Santa Ana?

There are 1 airlines that offer direct flights from Saint Louis to Santa Ana. Find out the list of airlines on Wego.